SETDB2 and infection: While the number of both T cell populations were similar in control and knockout lungs on day 8 post-infection, a 2-fold increase in CD8+ T cells (6.54 ± 1.05 x 105 vs. 11.80 ± 1.47 x 105; p<0.01) was observed on day 10 in mice lacking Setdb2 (Fig 7A).