They reported that human colon cancer tissues and the colon cancer cell line Colo205 contain cancer-associated glycosphingolipids with dimeric Lewis A antigens (Galβ1–3(Fucα1–4)GlcNAcβ1–3Galβ1–3(Fucα1–4)GlcNAc) and B3GNT3 is likely to be the most probable candidate involved in the biosynthesis of the backbone structure of dimeric sialyl Lewis A (Galβ1–3GlcNAcβ1–3Galβ1–3GlcNAc). The gene discussed is B3GNT3; the disease is malignant colon neoplasm.