HPRT1 and Spastic paraplegia: Crossing our putamen NBIA-enriched modules with genes associated with at least two of those core HPO terms and an OMIM entry, we found genes associated with Parkinson's disease (SYNJ1-OMIM#604297), spastic paraplegia (BSCL2-OMIM#606158), Lesch-Nyhan syndrome (HPRT1-OMIM#308000), and other neurological diseases/syndromes (ATP6AP2-OMIM#300556, L1CAM-OMIM#308840), among highly interconnected genes (≥ 95th quantile) of the brown module.