The downregulated genes comprised the thioredoxin-interactin protein (TXNIP), whose downregulation was also observed in HUVEC (Kawashiro et al. 2009) and H295R adrenocortical carcinoma cells (Song et al. 2009) after exposure to polybrominated diphenyl ethers. This evidence concerns the gene TXNIP and adrenal cortex carcinoma.