Here, contrary to previous reports, none of hyperferritinemia, hyperbilirubinemia, high C-reactive protein level, or hemophagocytosis features on bone marrow aspirations was significantly associated with higher mortality.3 The advance in age, the SOFA score at ICU admission, lymphoma-related HLH, or HLH of unknown origin were also associated with higher risks of hospital mortality. Here, CRP is linked to isolated hyperferritinemia.