Here, we tested whether the recombination of B-type stem/progenitor cells, using GLAST::CreERT2 mice to recombine the tumour suppressor genes Pten and p53 (GLAST::CreERT2;PtenloxP/loxP;p53loxP/loxP) would give rise to similar tumours. Here, TP53 is linked to neoplasm.