POU5F1 and Ventriculomegaly: Both LVID;d and LVID;s were depressed in mice receiving control siRNA-treated CSCs as compared with mice receiving PBS injection post MI (Fig. 2a, b, e), suggesting that CSC engraftment prevented left ventricular dilation in the MI heart, but the LV diameters were not reduced in mice receiving Oct3/4 siRNA-treated CSC injections.