Seemly lower TGFB1 mRNA levels were observed in the tumours from regional lymph node-negative patients and in the triple-negative tumours, and lower TGFBR1 mRNA levels were observed in HER2 negative tumours (Fig. 2a, d and e), though the corresponding p-values did not survive Bonferroni correction. The gene discussed is TGFBR1; the disease is neoplasm.