Treatment of the cells with TSA alone also induced re-expression of maspin gene mRNA (mammary serine protease inhibitor) in MCF-7, T-47D, and ZR-75-1 breast cancer cell lines, but re-expression has not been observed in MDA-MB-231 and SK-BR-3 breast cancer cell lines. The gene discussed is SERPINB5; the disease is breast carcinoma.