ALB and Ascites: Yuen et al. [23] suggested that the prognostic factors in CHB with spontaneous severe AE not receiving antiviral treatment included pre-existing cirrhosis, high Child-Pugh score, low albumin level, high bilirubin level, prolonged prothrombin time (PT), and low platelet count, while prognostic factors for subsequent monitoring were high peak bilirubin level, long peak PT, duration to reach peak PT, development of encephalopathy, and presence of ascites.