TSC2 and tuberous sclerosis: Two of our cases, neither of whom had a clinical diagnosis of TSC, had stop variants in exon 25 (TSC2 c.2859dup, p.K954Qfs*6) and exon 31 (TSC2 c.3837C>G, p.Y1279*), respectively, that would necessitate a diagnosis of TSC according to the updated TSC diagnostic criteria [Northrup et al., 2013].