Hence, we evaluated matched serum of the endometrial cancer tissue specimens using a multiplex kit that detects angiopoietin-2 (Ang-2), follistatin, granulocyte-colony stimulating factor (G-CSF), hepatocyte growth factor (HGF), interleukin-8 (IL-8), platelet-derived growth factor (PDGF)-BB, platelet endothelial cell adhesion molecule (PECAM-1) and VEGF. This evidence concerns the gene HGF and endometrial cancer.