ERBB2 and neoplasm: As an example, trastuzumab, which is a humanized monoclonal antibody directed against human epidermal growth factor receptor type 2 (HER2), can be decomposed as tras-tu—zu—mab, in which -tu- indicates that it targets tumour cells, and -zu- indicates that it is humanized (derived from a non-human antibody, which is then engineered to be more homologous with human antibodies).