To initiate research on this front we performed meta-analysis of DNA sequencing and transcriptomic data from large cohorts of human lung adenocarcinoma deposited in TCGA (Figure 8), and confirmed previous findings on the high frequency of LKB1 inactivation in lung adenocarcinoma, which scored at 18.7% [22, 47]. This evidence concerns the gene STK11 and lung adenocarcinoma.