The dominance of Kd-149.5 tetramer+ CD8 T cells (S2A Fig) and Kd-149.5-restricted CTL activity at day 21 (S2B Fig) also occurs in mice infected with a sub-lethal dose (100 PFU) of ECTV-WT and is therefore not unique to ECTV-IFN-γbpΔ infection. This evidence concerns the gene CD8A and infection.