In line with this, the commonly studied VDR SNP FokI (in low LD with rs7968585) appears to be associated with T2D, at least in Asian populations [13, 18] and cancer [44, 45]; and the SNPs ApaI, BsmI, as well as TaqI appear to be associated with CAD [22–24] as well as with cancer [44, 45] and cancer-related mortality [21]; and some Cdx2 (in low LD with rs7968585) haplotypes appear to be associated with increased risk of cancer [46]. Here, CDX2 is linked to type 2 diabetes mellitus.