Positively associated genes included several genes involved in cell cycle progression; among others CCNB1, CCNB2, CENPA, CDC20 and CDC25B, oocyte maturation and meiosis, metabolism; including pituitary tumour-transforming (PTTG1, PTTG2 and PTTG3) and mevalonate (diphospho) decarboxylase (MVD) involved in cholesterol synthesis, as well as the cell-cycle regulating transcription factor E2F1 and several of its targets. The gene discussed is CDC25B; the disease is pituitary tumor.