In addition, statistical analysis of mRNA expression between methylated and unmethylated tissues revealed that in SALL3 methylated tissues, the mRNA of SALL3 was higher than in unmethylated tissues(p<0.05).Taken together, the results demonstrated SALL3 hypermethylation contributed to the down-regulation of gene expression in transcription level in cervical cancer. This evidence concerns the gene SALL3 and cervical carcinoma.