The overall detected 10 cases with TP53 deletion (Table 2) were further studied by iFISH using probes IKZF3 in 17q12, UNC13D in 17q25.1, and subtelomeric probes (17pter and 17qter; Figure 1(a)); furthermore iFISH-probes for the most frequent aberrations in CLL and, in part, aCGH (case 3; Figure 1(b)) have been applied in those cases, as specified by Alhourani et al. (2014). This evidence concerns the gene TP53 and B-cell chronic lymphocytic leukemia.