Resistance of OSCSCs or MP2 induced by fixed NK cells treated with IL-2 + anti-CD16mAb + sAJ2 correlated with the increase in the surface expressions of CD54 and MHC-I on OSCSCs (Figure 3B) and CD54, B7H1, and MHC-1 on MP2 (Figure S6B in Supplementary Material), and the addition of both anti-TNF-α and anti-IFN-γ to IL-2 + anti-CD16mAb + sAJ2-treated NK cells before their use to treat tumor cells inhibited the upregulation of these receptors on tumor cells. The gene discussed is IFNG; the disease is neoplasm.