Similarly, an ARACNe-inferred glioblastoma GRN was created and used by Chen et al. (2014) to identify two master regulators, C/EBPβ and C/EBPδ that are known to be involved in mesenchymal subtype of glioblastoma patients (Carro et al., 2010). The gene discussed is CEBPB; the disease is glioblastoma.