Interestingly, EGCG also has inhibitory properties on the kinase activity of DYRK1A (Bain et al., 2003; Adayev et al., 2006; Wang et al., 2012), a DS candidate whose overabundance is associated with DS neurocognitive symptoms and neurodegenerative phenotypes (Becker et al., 2014). This evidence concerns the gene DYRK1A and Dravet syndrome.