MAPT and Alzheimer disease: Since tau has been localized in association with Golgi membranes, where it could serve as a link between these structures and microtubules (Farah et al., 2006), and the GA undergo widespread structural alterations in neurons of patients and animal models of AD (Gonatas et al., 1998b; Liazoghli et al., 2005; Hu et al., 2007), in the present study we analyze whether the alterations of the GA in cortical neurons of hibernating hamsters during torpor might be correlated with the accumulation of hyperphosphorylated tau.