We did not detect TMPRSS2-ERG gene fusion in this patient, however, we found that TMPRSS2 gene was fused with other partners including ETV4, TRIP4, and PNPO in the visit 1 patient tumor tissue, and all these TMPRSS2 involved fusion events were rediscovered in PDXs (S7 Table). The gene discussed is TRIP4; the disease is neoplasm.