ITGA1 and type 2 diabetes mellitus: In adults T2D has been associated with high BMD [16,17] and Billings et al. [20] identified Integrin, Alpha 1 (ITGA1) as a new locus candidate, capable of influencing both fasting glucose and BMD, thus pointing to a possible explanation for the epidemiological observations linking T2D diabetes and BMD/osteoporosis.