However, since most skin tumors harbor P53 deleterious mutations (IARC TP53 database, R17 November 2013, www.p53.iarc.fr), [35] we aimed at measuring the impact of P53 abrogation in WT and NBCCS keratinocytes exposed to NBCCS fibroblasts in organotypic invasion assays. Here, TP53 is linked to skin neoplasm.