Strong protective associations were detected between bariatric surgery and T2DM onset (HR = 0.68, 95% CI 0.55–0.83), first treatment with an OAD (HR = 0.26, 95% CI 0.18–0.37), first treatment with insulin (HR = 0.22, 95% CI 0.11–0.43), hypertension onset (HR = 0.35, 95% CI 0.27–0.45), angina onset (HR = 0.59, 95% CI 0.40–0.87), MI (HR = 0.28, 95% CI 0.10–0.74), and obstructive sleep apnoea onset (HR = 0.55, 95% CI 0.37–0.82) (see Table 3). This evidence concerns the gene INS and angina pectoris.