Patients with NAFLD/NASH present several alterations in redox and inflammatory markers, such as increase of high sensitivity C-reactive protein (hsPCR) [204]; AGE [205], which may result from a variety of reactions (direct way) or by mechanism involving the hydroxy radical-mediated oxidation of lipids (indirect way) [206] and MDA [207]. The gene discussed is CRP; the disease is metabolic dysfunction-associated steatotic liver disease.