In summary, when compared to an unchanging 22 nt Homo sapien miRNA-183 and the ~120 nucleotide structural 5S ribosomal RNA (5S rRNA; 5SRNA) and other control markers within the same sample, an inducible, NF-κB-regulated six member miRNA family consisting of miRNA-7, miRNA-9, miRNA-34a, miRNA-125b, miRNA-146a and miRNA-155 are found to be amongst the most consistently up-regulated pro-inflammatory miRNAs found in AD brain when compared to age-matched controls (Table 1; Figure 1 and Figure 2). The gene discussed is NFKB1; the disease is Alzheimer disease.