NFKB1 and Alzheimer disease: Inhibition of NF-κB activation and signaling and/or the individual quenching of the pathogenic up-regulation of these six miRNAs could provide novel therapeutic benefit for the clinical management of AD, however what specific NF-κB inhibition strategies or whether they can be utilized in some beneficial combinatorial approach remain open to very active investigation [57,58,59,60,61,62].