Administration of EGCG (50–100 mg/kg/day) for 4 weeks reduced tumor weight, decreased capillary density in the tumors, diminished tumor VEGF expression without affecting body weight and angiogenesis in the heart in C57BL/6J mice with E0771 mouse breast cancer cells implanted in the mammary gland fat pad [239]. The gene discussed is VEGFA; the disease is breast cancer.