One large systematic review of bariatric surgery after T2DM [37], comprising of 621 studies with 135,246 patients, revealed that for subjects with a mean age of 40.2 years and BMI of 47.9 kg/m2, bariatric surgery offered a decrease in BMI by 14.5 kg/m2, and within 2 years, there was a drop in HbA1c by 2.13 % and a drop in insulin dose by 97.98 units. Here, INS is linked to type 2 diabetes mellitus.