Additionally, studies have reported that the receptor genes for various forms of vitamin D that can be synthesized in the body are associated with cognitive impairment as well as depressive symptoms [40], that vitamin D regulates the gene expression of nerve growth factor, which has an important effect on neurotransmission [41], and that vitamin D can act as a neuroprotective factor in suppressing the oxidation and denaturation of neurons through its antioxidant activity [42, 43]. The gene discussed is NGF; the disease is Cognitive impairment.