Results of age-adjusted logistic regression model showed additionally that study members classified as having sarcopenia using the FNIH definition were more likely to be in the upper tertile of IR (odds ratio (OR) = 2.27, 95 % CI 1.10–4.68), CRP (OR = 3.03, 95 % CI 1.44–6.35) and IL-6 (OR = 2.97, 95 % CI 1.39–6.32). The gene discussed is IL6; the disease is sarcopenia.