NOS2 and cirrhosis of liver: Based on the previous studies that indicate that nitric oxide (NO) plays an important role in the systemic and renal alterations of liver cirrhosis, in this study, we used aminoguanidine (AG), a preferential inhibitor of inducible nitric oxide synthase (iNOS), to evaluate the role of this NOS isoform in the pathogenesis of liver cirrhosis and its subsequent alteration in renal function.