Hsiehet al. (2004) showed that the Tp53Arg72Pro polymorphism is not a risk factor for UL in Taiwanese women. Similar to theresults of our study, carriage of the Tp53 codon72 polymorphism couldbe associated with UL susceptibility in a Caucasian population (Germany) and maycontribute to the pathology of leiomyoma (Denschlaget al., 2005). In another study on several polymorphismsin the promoter region of the Tp53 gene, a −216C and a −103G SNP werefound to be associated with the development of UL (Hsiehet al., 2007). Here, TP53 is linked to leiomyoma.