The toll-like receptor 7 (TLR7) agonist IMQ is used for topical treatment of actinic keratoses, superficial basal cell carcinomas, and human papilloma virus-caused genital and perianal warts[12,13], but it was found that in the treatment of people who are prone to psoriasis, the occurrence of psoriasis was detected[14]. The gene discussed is TLR7; the disease is psoriasis.