Furthermore, Forkhead box O transcription factors (Foxo) [20] and muscle-specific E3 ubiquitin ligases, such as muscle RING-finger 1 (MuRF1) and Atrogin-1/muscle atrophy F-box (MAFbx) [21], which mediates protein degradation through the ubiquitin proteasome system (UPS), are critical players regarding the functional outcome of the target organ following peripheral nerve injury. This evidence concerns the gene FBXO32 and peripheral nerve injury.