KRAS and metastatic malignant neoplasm in the lymph nodes: However, no significant relationship was observed between KRAS mutations and sex (P = 0.288), age (P = 0.185), depth of invasion (P = 0.694), lymph node metastasis (P = 0.410), distant metastasis (P = 0.103) or TNM stage (P = 0.209).