It is possible that Black African HIV-positive patients may have been exposed more commonly to LEV for appropriate indications, such as those already mentioned above (urinary or digestive infections) because they had more pronounced immune depression (lower CD4 counts) and a higher risk of pneumonia, or they may have been exposed to inappropriate prescription of fluoroquinolones [15, 20, 21, 24, 25]. The gene discussed is CD4; the disease is pneumonia.