Univariate analysis revealed that old age, the presence of solid tumors, a high Charlson co-morbidity index, a longer interval from admission to the onset of SAB, the presence of persistent bacteremia, septic shock, not receiving effective antibiotic treatment within 48 hours after the onset of SAB, thrombocytopenia, a high CRP level, bacteremia caused by HA-MRSA-S, and bacteremia caused by MRSA isolates carrying the type II or III SCCmec element to be associated with in-hospital mortality. This evidence concerns the gene CRP and bacterial infectious disease with sepsis.