ERBB2 and neoplasm: We observed strong membranous staining for HER2 (Figure 1A) in 25 of 1914 (1.3%) stage II–III tumours and 29 of 1342 (2.2%) stage IV tumours tested [18 of 888 (2.0%) in FOCUS; 11 of 454 (2.4%) in PICCOLO].