In PC cells, testosterone and 1,25-dihydroxyvitamin D3 (1,25(OH)2D3)-induced miR-17/92 downregulation was reported to alleviate the miRNA-mediated inhibitory effect on PPARA mRNA, thereby increasing PPARA transcript stability, promoting neutral lipid synthesis, and retarding tumor progression [161]. This evidence concerns the gene PPARA and neoplasm.