We modeled the relationship between MAOB levels and Sp1 and Sp3 for the GBM and non-GBM populations and found that we could discern two general relationships, and that if we treated four of the GBM's as astrocytic glioma, the relationship became more pronounced; the 4 GBM's that appear to be more typical of astrocytic glioma than the general GBM population are shown in Figure 5A–5D as red highlighted black diamonds. The gene discussed is SP3; the disease is glioblastoma.