Since the correlation between BRCA1/2 germline and higher somatic mutation rate may be characteristic of the basal subtype breast cancer, we compared the mutation frequency of basal cases with BRCA1/2 germline truncation to basal cases without BRCA1/2 germline truncation and found the former have significantly higher mutation rate (Supplementary Fig. 4, Wilcoxon rank-sum test, P=9e-4). This evidence concerns the gene BRCA1 and breast carcinoma.