This is the first report considering the association of the risk of larynx cancer and SNPs of the following polymorphisms: DROSHA (rs6877842), DGCR8 (rs3757, rs417309, and rs1640299), RAN (rs14035), XPO5 (rs11077), DICER1 (rs13078 and rs3742330), and TARBP2 (rs784567). The gene discussed is RAN; the disease is larynx cancer.