The beneficial improvements in FABP4, insulin resistance, TAG levels, abdominal fat, and the differential regulation of FABP with NC and the FVJC supplementation suggest that carotenoids, along with other polyphenols, may play a role in the regulation of abdominal adiposity, similar to that reported in animal models(32,41), and warrant further exploration in the paediatric population(19,42). Here, FABP4 is linked to Insulin resistance.