The present project was designed to test the feasibility of aptamer SYL3C as a molecular diagnostic/prognostic tool by evaluating its binding ability in the detection of EpCAM expression based on 170 cases of EC and precancerous lesions, as well as 20 cases of EC series samples (normal, borderline, cancer nest and metastasis), using immunofluorescence imaging analysis. This evidence concerns the gene EPCAM and cancer.