Nevertheless, despite not characterising glycosylation at Asn146 we still conclude that IgE glycosylation does not change in allergy and PGM3 related hyper IgE syndrome, because we have both the overall glycan profile of IgE and glycoproteomic data from 6 of the 7 glycosylation sites in the glycoproteomic data. Here, IGHE is linked to Allergy.