Patients with acute cholecystitis may demonstrate, albeit rarely, ECG changes and laboratory abnormalities (such as positive H-FABP) that are suggestive of coronary ischemia; however, considering that we could diagnosed acute cholecystitis within 1 day after the admission, careful physical examination as well as routine laboratory tests of the hepatobiliary systems may able to avoid the delay of diagnosis of this gastroenterological disorder that might cause critical complications. This evidence concerns the gene FABP3 and Cholecystitis, Acute.