CCL2 and cystic fibrosis: A double-blind, placebo-controlled clinical study has been designed to determine the effects of CF on levels of CRP, total cholesterol (TC), LDL cholesterol, triglycerides, interleukin-1β (IL-1β), interleukin-6 (IL-6), and MCP-1 (monocyte chemoattractant protein-1) [7].